Simulations Plus | January 16, 2023
Simulations Plus, Inc. recently announced that its DILIsym Services (DSS) division released DILIsym® version X (DSX) Beta, the latest iteration of its flagship quantitative systems toxicology (QST) software for predicting and investigating drug-induced liver injury (DILI).
DILIsym modeling aids vital drug development decisions by prevising the potential DILI risk of new drug candidates. The modeling also identifies the biochemical events that contribute to DILI caused by a medicine and can thus predict specific subgroups of patients who are more likely to get DILI from that drug.
DILIsym modeling information helps guide go/no-go decisions on big drug development projects, potentially averting the terrible financial impacts of failed clinical trials or better offering reassurance that DILI will not be an insurmountable barrier to FDA approval. Over the past 12 years, the DILIsym Services division has coordinated the DILI-sim Initiative, a public-private partnership that helped guide the development of the DILIsym software package.
Some of the substantial updates for DSX include:
A complete software redesign that includes command line and graphical interface options and server/cloud computing capability (HPGL)
Four new exemplar compounds included with varying clinical presentations:
PF-04895162 (Generaux 2019)
Two new SimCohorts that include variability in susceptibility to liver injury and biomarker-related parameters (ALT and bilirubin)
About Simulations Plus
Simulations Plus, Inc. is a leading drug discovery/development software developer and preclinical and clinical pharmacometric consulting services provider for regulatory submissions and quantitative systems pharmacology models for drug-induced liver, kidney, and nonalcoholic fatty liver disease. Its software is licensed and applied to drug research by major pharmaceutical, biotechnology, chemical, and consumer goods companies as well as regulatory agencies worldwide. With its subsidiaries, Cognigen, DILIsym Services, and Lixoft, Simulations Plus offers solutions that bridge machine learning, physiologically based pharmacokinetics, quantitative systems pharmacology/toxicology, and population PK/PD modeling approaches.
Zayo Group | January 17, 2023
Zayo Group Holdings, a global communications infrastructure platform, announced the deployment of a new 400G-enabled route between Paris and Marseille. This new route includes the first-in-market network hardening of this critical route using next-generation fiber technologies. This will make it easier and safer for businesses to move high-bandwidth traffic from these top ten global internet hubs, where traffic is growing quickly.
In the next three years, Marseille is expected to go from being the seventh largest internet hub in the world to the fifth largest. With the completion of six new undersea cables, including key gateways to Africa, Asia, and the Middle East, capacity needs in Marseille are expected to quadruple by 2026.
Zayo Group Holdings’ new 400G-enabled route, connecting Paris and Marseille, is designed to help meet this increasing capacity demand and provide more secure ways for enterprises to transport high-bandwidth traffic from these global internet hubs.
The new route is expected to have a total capacity of 24 terabytes per fiber pair and important tri-location options for businesses to make sure they can connect securely and reliably to the rest of Europe and the US. With the new route in place, Zayo Group Holdings will be well-positioned to meet the capacity demands of the increasing high-bandwidth traffic between Paris and Marseille.
About Zayo Group Holdings, Inc.
Zayo Group Holdings, Inc. is a global communications infrastructure platform, offering fiber and transport, packet, and managed edge services. Zayo owns and operates a 137,000-mile-long Tier 1 IP backbone across North America and Europe. By giving this mission-critical bandwidth to its top customers in the wireless, hyperscale, media, tech, and finance industries, Zayo is helping to fuel the innovations that are changing society.
HYPER-CONVERGED INFRASTRUCTURE, APPLICATION STORAGE
Kofax | March 13, 2023
Kofax, a leading Intelligent Automation platform for digital workflow transformation, recently announced the latest version of Printix, its cloud print management SaaS offering. Printix helps organizations with their all-cloud strategies and eliminates the need for print server infrastructure by giving them a full print infrastructure and environment that improves efficiency and productivity and saves money.
Printix supports Single Sign-on (SSO) with Microsoft Azure Active Directory and is deployable with Microsoft Endpoint Manager. The product is made to be scalable and can handle any number of users, multi-function devices (MFDs) and printers for mobile printing, secure and flexible printing, and document capture workflows.
Key features of Kofax Printix summarized:
Next-generation capture: scan or capture documents to the Printix Cloud and generate PDFs
Simple print management : manage centrally, the printers from web browsers; connect new printers from a computer, tablet or a smartphone
Print-later and print-anywhere capabilities: Users can send documents to a printer from the Printix app when they get to the printer or release documents at any time with the Print Later feature.
Automatic printer discovery: As users come and go, Printix lets users automatically find the print network, integrate printers and drivers, and set up or get rid of printers and print queues
Advanced Microsoft integration: Printix works well with Microsoft Azure Active Directory and can be easily set up with EndPoint Manager and Single Sign-On. This gives users, confidence and takes away the need for IT and administration work.
Complete support for network printers: Users can print to any printer from any device, as the system supports a diversified range of devices from different manufacturers
Rod Hughes, Vice President, Product Strategy at Kofax said, "This edition of Printix completely eliminates print servers from network infrastructure and replaces them with a secure, cloud-managed print infrastructure with next-generation integrated capture."
(Source – Business Wire)
Kofax founded in 1985 and headquartered in Irvine (California), Kofax digitally transform content-intensive workflows. They provide a software platform for intelligent automation and a number of solutions that are meant to digitally change business workflows. Their software platform uses advanced technologies like cognitive capture, analytics, robotic process automation (RPA), process orchestration, and mobile capabilities to help businesses become more competitive, grow, and make more profits. Their platform also helps businesses become more resilient by making it easy for them to adjust quickly to changing market conditions and reduce compliance risks.